Gut Microbiome and Associated Metabolites Following Bariatric Surgery and Comparison to Healthy Controls.

ABSTRACT: The gut microbiome plays a significant role in regulating the host's ability to store fat, which impacts the development of obesity. This observational cohort study recruited obese adult men and women scheduled to undergo sleeve gastrectomy and followed up with them 6 months post-surgery to analyse their microbial taxonomic profiles and associated metabolites in comparison to a healthy control group. There were no significant differences in the gut bacterial diversity between the bariatric patients at baseline and at follow-up or between the bariatric patients and the cohort of healthy controls. However, there were differential abundances in specific bacterial groups between the two cohorts. The bariatric patients were observed to have significant enrichment in Granulicatella at bas

SUBMITTER: Ahmad AF 

PROVIDER: S-EPMC10223326 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature