Agua Salud Alphavirus Infection, Dissemination and Transmission in <i>Aedes aegypti</i> Mosquitoes.

ABSTRACT: Mosquitoes are competent vectors for many important arthropod-borne viruses (arboviruses). In addition to arboviruses, insect-specific viruses (ISV) have also been discovered in mosquitoes. ISVs are viruses that replicate in insect hosts but are unable to infect and replicate in vertebrates. They have been shown to interfere with arbovirus replication in some cases. Despite the increase in studies on ISV-arbovirus interactions, ISV interactions with their hosts and how they are maintained in nature are still not well understood. In the present study, we investigated the infection and dissemination of the Agua Salud alphavirus (ASALV) in the important mosquito vector Aedes aegypti through different infection routes (per oral infection, intrathoracic injection) and its transmission. W

SUBMITTER: Jagtap SV 

PROVIDER: S-EPMC10223791 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature