Clinical Presentation of Parvovirus B19 Infection in Adults Living with HIV/AIDS: A Case Series.

ABSTRACT: Parvovirus B19 (B19V) infection varies clinically depending on the host's immune status. Due to red blood cell precursors tropism, B19V can cause chronic anemia and transient aplastic crisis in patients with immunosuppression or chronic hemolysis. We report three rare cases of Brazilian adults living with human immunodeficiency virus (HIV) with B19V infection. All cases presented severe anemia and required red blood cell transfusions. The first patient had low CD4⁺ counts and was treated with intravenous immunoglobulin (IVIG). As he remained poorly adherent to antiretroviral therapy (ART), B19V detection persisted. The second patient had sudden pancytopenia despite being on ART with an undetectable HIV viral load. He had historically low CD4⁺ counts, fully responded t

SUBMITTER: Mendes-de-Almeida DP 

PROVIDER: S-EPMC10223798 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature