Variation in central venous oxygen saturation to evaluate fluid responsiveness: a systematic review and meta-analysis.

ABSTRACT:

Background

Since oxygen content and oxygen consumption typically remain unchanged within a short period, variation in central venous oxygen saturation (ΔScvO₂) during fluid challenge can theoretically track the changes in cardiac output (CO). We conducted this meta-analysis to systematically assess the diagnostic performance of ΔScvO₂ during a fluid challenge for fluid responsiveness in mechanically ventilated patients receiving volume expansion.

Methods

Electronic databases were systematically searched to identify relevant studies published before October 24, 2022. As the cutoff value of ΔScvO₂ was expected to vary across the included studies, we estimated the area under the hierarchical summary receiver operating characteristic curve (AUHSR

SUBMITTER: Pan J 

PROVIDER: S-EPMC10223907 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature