Pleural Fluid Resolution Is Associated with Improved Survival in Patients with Malignant Pleural Effusion.

ABSTRACT: Malignant pleural effusion is associated with a poor prognosis and, while risk stratification models exist, prior studies have not evaluated pleural fluid resolution and its association with survival. We performed a retrospective review of patients diagnosed with malignant pleural effusion between 2013 and 2017, evaluating patient demographics, pleural fluid and serum composition, and procedural and treatment data using Cox regression analysis to evaluate associations with survival. In total, 123 patients were included in the study, with median survival from diagnosis being 4.8 months. Resolution of malignant pleural fluid was associated with a significant survival benefit, even when accounting for factors such as placement of an indwelling pleural catheter, anti-cancer therapy, pleural fl

SUBMITTER: MacRosty CR 

PROVIDER: S-EPMC10223971 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature