Cluster analysis of angiotensin biomarkers to identify antihypertensive drug treatment in population studies.

ABSTRACT:

Background

The recent progress in molecular biology generates an increasing interest in investigating molecular biomarkers as markers of response to treatments. The present work is motivated by a study, where the objective was to explore the potential of the molecular biomarkers of renin-angiotensin-aldosterone system (RAAS) to identify the undertaken antihypertensive treatments in the general population. Population-based studies offer an opportunity to assess the effectiveness of treatments in real-world scenarios. However, lack of quality documentation, especially when electronic health record linkage is unavailable, leads to inaccurate reporting and classification bias.

Method

We present a machine learning clustering technique to determine the potential of measured RAAS b

SUBMITTER: Arisido MW 

PROVIDER: S-EPMC10224304 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature