Clustered Cases of Waterborne Hepatitis E Virus Infection, France.

ABSTRACT: The identification of seven cases of hepatitis E virus infection in a French rural hamlet in April 2015 led to investigations confirming the clustering and identifying the source of the infection. Laboratories and general practitioners in the area actively searched for other cases based on RT-PCR and serological tests. The environment, including water sources, was also checked for HEV RNA. Phylogenetic analyses were performed to compare HEV sequences. No other cases were found. Six of the seven patients lived in the same hamlet, and the seventh used to visit his family who lived there. All HEV strains were very similar and belonged to the HEV3f subgenotype, confirming the clustering of these cases. All the patients drank water from the public network. A break in the water supply to the ham

SUBMITTER: Lhomme S 

PROVIDER: S-EPMC10224386 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature