Do patients with metastatic pancreatic adenocarcinoma to the lung have improved survival?

ABSTRACT:

Introduction

Pancreatic ductal adenocarcinoma (PDAC) is a genetically heterogeneous disease often diagnosed with synchronous metastatic disease involving the liver. Tumors with extra-abdominal spread that bypass the liver are thought to represent a unique molecular subgroup and those with isolated pulmonary metastatic disease are thought to have a more favorable clinical phenotype.

Method

We conducted a retrospective review of patients with pathologically confirmed PDAC treated between the years 2007 and 2020 at a Scripps Health hospital. The final study sample (N = 205) included patients with isolated pulmonary metastasis (IL), isolated liver metastasis or synchronous liver and lung metastasis (LL), or metastasis to any site other than the liver or lung (NLL). Primary endpo

SUBMITTER: Ebrahimi A 

PROVIDER: S-EPMC10225201 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature