Association of vaspin rs2236242 with type 2 diabetes mellitus and obesity: a meta-analysis of case-control studies.

ABSTRACT:

Background

Elevated circulating vaspin levels is linked with type 2 diabetes mellitus (T2DM) and obesity. The genetic basis of the association between vaspin rs2236242 and T2DM and obesity is still being investigated. We executed a meta-analysis to evaluate the magnitude of effect caused by vaspin rs2236242 on T2DM and obesity.

Methods

We searched Pubmed, Embase, MEDLINE, Scopus, Web of Science, and Google Scholar for relevant articles published up to 19 February 2022. Data were extracted and summary estimates of the association between vaspin rs2236242 and T2DM and obesity were assessed. Odds ratios (ORs) and confidence intervals (CIs) were used to measure the effect.

Results

This meta-analysis included 2206 cases and 2715 controls in the T2DM cohort, meanwhile 271 c

SUBMITTER: Zain SM 

PROVIDER: S-EPMC10225408 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature