Chicken adaptive response to nutrient density: immune function change revealed by transcriptomic analysis of spleen.

ABSTRACT: Feed accounts for the largest portion (65-70%) of poultry production costs. The feed formulation is generally improved to efficiently meet the nutritional needs of chickens by reducing the proportion of crude protein (CP) and metabolizable energy (ME) levels in the diet. Although many studies have investigated the production performance during dietary restriction, there is a lack of research on the mechanisms by which immune cell function is altered. This study examined the effects of ME and CP restriction in the chicken diet on serum immunoglobulins and expression of immune function genes in spleen. Changes in serum immunoglobulins and immune-related gene expression were analyzed in 216 YS-909 broilers fed with 9 different dietary treatments, including experimental treatment diets contain

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC10225541 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature