Hospital and community wastewater as a source of multidrug-resistant ESBL-producing Escherichia coli.

ABSTRACT:

Introduction

Hospitals and wastewater are recognized hot spots for the selection and dissemination of antibiotic-resistant bacteria to the environment, but the total participation of hospitals in the spread of nosocomial pathogens to municipal wastewater treatment plants (WWTPs) and adjacent rivers had not previously been revealed.

Methods

We used a combination of culturing and whole-genome sequencing to explore the transmission routes of Escherichia coli from hospitalized patients suffering from urinary tract infections (UTI) via wastewater to the environment. Samples were collected in two periods in three locations (A, B, and C) and cultured on selective antibiotic-enhanced plates.

Results

In total, 408 E. coli isolates were obtained from patien

SUBMITTER: Davidova-Gerzova L 

PROVIDER: S-EPMC10225658 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature