Effects of dulaglutide combined with insulin degludec on glucose fluctuations and appetite in type 2 diabetes

ABSTRACT:

Introduction

The aim of this study was to describe appetite and glucose fluctuation in type 2 diabetes mellitus patients initiating treatment with dulaglutide combined with insulin degludec.

Methods

This retrospective study of patients identified adults starting treatment with once-weekly (QW) dulaglutide combined with insulin degludec (experimental group) or insulin degludec alone (control group). Patients were followed for up to 6 months from treatment initiation. The clinical characteristics of patients, treatment patterns, CGM data, and appetite scores were obtained for the two groups.

Results

A total of 236 patients were included in this study. SDBG, MAGE, LAGE, and PPGE of the experimental group were lower than the control group’s (P < 0.05). The proportion

SUBMITTER: Huang J 

PROVIDER: S-EPMC10225703 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature