Role of SEC14-like phosphatidylinositol transfer proteins in membrane identity and dynamics.

ABSTRACT: Membrane identity and dynamic processes, that act at membrane sites, provide important cues for regulating transport, signal transduction and communication across membranes. There are still numerous open questions as to how membrane identity changes and the dynamic processes acting at the surface of membranes are regulated in diverse eukaryotes in particular plants and which roles are being played by protein interaction complexes composed of peripheral and integral membrane proteins. One class of peripheral membrane proteins conserved across eukaryotes comprises the SEC14-like phosphatidylinositol transfer proteins (SEC14L-PITPs). These proteins share a SEC14 domain that contributes to membrane identity and fulfills regulatory functions in membrane trafficking by its ability to sense, bind

SUBMITTER: Montag K 

PROVIDER: S-EPMC10225987 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature