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The Differential Diagnostic Value of Radiomics Signatures Between Single-Nodule Pulmonary Metastases and Second Primary Lung Cancer in Patients with Colorectal Cancer.


ABSTRACT:

Background

Differential diagnosis of single-nodule pulmonary metastasis (SNPM) and second primary lung cancer (SPLC) in patients with colorectal cancer (CRC) prior to lung surgery is relatively complex. Radiomics is an emerging technique for image information analysis, while it has not yet been applied to construct a differential diagnostic model between SNPM and SPLC in patients with CRC. In the present study, we aimed to extract radiomics signatures from thin-section computed tomography (CT) images of the chest. These radiomics signatures were combined with clinical features to construct a composite differential diagnostic model.

Method

A total of 91 patients with CRC, including 66 patients with SNPM and 25 patients with SPLC, were enrolled in this study. Patients were ran

SUBMITTER: Yu Y 

PROVIDER: S-EPMC10226291 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature