Lipoid Congenital Adrenal Hyperplasia With a Novel StAR Gene Mutation.

ABSTRACT: Lipoid congenital adrenal hyperplasia (LCAH) is characterized by disturbance of adrenal and gonadal steroidogenesis (OMIM:201710). It is caused by mutation in the Steroidogenic Acute Regulatory Protein (StAR). We report a classic case of LCAH in a neonate (46, XY) with phenotypic female genitalia who presented with significant salt loss with a novel homozygous variant mutation c.745-1G>C p. in StAR gene.

SUBMITTER: Bakkar AA 

PROVIDER: S-EPMC10226314 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature