High Triglyceride Variability Increases the Risk of First Attack of Acute Pancreatitis.

ABSTRACT:

Introduction

Hypertriglyceridemia is the third most common etiology of acute pancreatitis. Whether triglyceride variability, independent of absolute triglyceride levels, is a predictor of acute pancreatitis is unknown.

Methods

We identified 98,819 patients who were diagnosed with hyperlipidemia between January 1, 2007, and December 31, 2013, and had at least 1 triglyceride measurement annually for 4 consecutive years from the Chang Gung Research Database in Taiwan. Triglyceride variability, defined as variability independent of the mean, was calculated in the 4-year run-in period. The patients were stratified according to the quartiles of triglyceride variability and were followed until December 31, 2019, for first attack of acute pancreatitis.

Results

During a mean f

SUBMITTER: Tung YC 

PROVIDER: S-EPMC10226468 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature