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The Essential Function of miR-5739 in Embryonic Muscle Development.


ABSTRACT:

Background and objectives

Embryologically, mesodermal development is closely related to the development of various organs such as muscles, blood vessels, and hearts, which are the main organs that make up the body. However, treatment for mesoderm developmental disorders caused by congenital or acquired factors has so far relied on surgery and drug treatment for symptom relief, and more fundamentally, treatment for mesoderm developmental disorders is needed.

Methods and results

In our study, microRNA (miRNA), which plays an important role in the mesoderm development process, was identified and the developmental function was evaluated. miRNAs consist of small nucleotides, which act as transcription factors that bind to the 3' untranslated region and suppressed target gene expr

SUBMITTER: Lee JH 

PROVIDER: S-EPMC10226859 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature