Renal scintigraphy to predict persistent renal failure after acute kidney injury: an observational study.

ABSTRACT:

Introduction

Renal scintigraphy (RS) is occasionally performed to assess the risk of persistent renal failure (PRF) in patients with acute kidney disease (AKD). However, its diagnostic performance has never been assessed.

Methods

We identified all patients with AKD for whom RS was performed in our institution between 2010 and 2017. PRF was defined as persistently low (< 33% of baseline) estimated glomerular filtration rates (eGFR), 1 year after RS. Nuclear medicine specialists reviewed RS data and rated, for each patient, the likelihood of PRF ("PRF score"). We evaluated the performance to predict PRF (area under the ROC curve (AUC)) of RS-derived parameters such as renal accumulation index, accumulation slope, and new parameters derived from serial kidney activity counts. W

SUBMITTER: Altarelli M 

PROVIDER: S-EPMC10226915 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature