Dataset Information

The effect of an integrated palliative care intervention on quality of life and acute healthcare use in patients with COPD: Results of the COMPASSION cluster randomized controlled trial.

ABSTRACT:

Background

COPD causes high morbidity and mortality, emphasizing the need for palliative care.

Aim

To assess the effectiveness of palliative care in patients with COPD.

Design

Cluster randomized controlled trial (COMPASSION study; Netherlands Trial Register (NTR): NL7644, 07-04-2019). Healthcare providers within the intervention group were trained to implement palliative care components into routine COPD care. Patients completed questionnaires at baseline, after 3 and 6 months; medical records were assessed after 12 months. The primary outcome was quality of life (FACIT-Pal). Secondary outcomes were anxiety, depression, spiritual well-being, satisfaction with care, acute healthcare use, documentation of life-sustaining treatment preferences and place of death. Generalized linear mixed modelling was used for analyses.

Setting

Eight hospital regions in the Netherlands.

Participants

Patients hospitalized for an acute exacerbation of COPD and positive ProPal-COPD score.

Results

Of 222 patients included, 106 responded to the questionnaire at 6 months. Thirty-six of 98 intervention patients (36.7%) received the intervention. Intention-to-treat-analysis showed no effect on the primary outcome (adjusted difference: 1.09; 95% confidence interval: -5.44 to 7.60). In the intervention group, fewer intensive care admissions for COPD took place (adjusted odds ratio: 0.21; 95% confidence interval: 0.03-0.81) and strong indications were found for fewer hospitalizations (adjusted incidence rate ratio: 0.69; 95% confidence interval: 0.46-1.03).

Conclusions

We found no evidence that palliative care improves quality of life in patients with COPD. However, it can potentially reduce acute healthcare use. The consequences of the COVID-19 pandemic led to suboptimal implementation and insufficient power, and may have affected some of our findings.

SUBMITTER: Broese J

PROVIDER: S-EPMC10227092 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Publications

The effect of an integrated palliative care intervention on quality of life and acute healthcare use in patients with COPD: Results of the COMPASSION cluster randomized controlled trial.

Broese Johanna J van der Kleij Rianne Mjj RM Verschuur Els Ml EM Kerstjens Huib Am HA Bronkhorst Ewald M EM Engels Yvonne Y Chavannes Niels H NH

Palliative medicine 20230331 6

<h4>Background</h4>COPD causes high morbidity and mortality, emphasizing the need for palliative care.<h4>Aim</h4>To assess the effectiveness of palliative care in patients with COPD.<h4>Design</h4>Cluster randomized controlled trial (COMPASSION study; Netherlands Trial Register (NTR): NL7644, 07-04-2019). Healthcare providers within the intervention group were trained to implement palliative care components into routine COPD care. Patients completed questionnaires at baseline, after 3 and 6 mon ...[more]

PMID: 37002561

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Dataset Information

The effect of an integrated palliative care intervention on quality of life and acute healthcare use in patients with COPD: Results of the COMPASSION cluster randomized controlled trial.

Background

Aim

Design

Setting

Participants

Results

Conclusions

Publications

The effect of an integrated palliative care intervention on quality of life and acute healthcare use in patients with COPD: Results of the COMPASSION cluster randomized controlled trial.

Similar Datasets

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