Clinical trial simulations in pulmonary fibrosis: patient-focused insights and adaptations.

ABSTRACT:

Background

Patient recruitment and retention are a challenge when conducting clinical trials in patients with pulmonary fibrosis, including idiopathic pulmonary fibrosis and other interstitial lung diseases. This study aimed to understand and address the barriers associated with trial participation for these populations.

Methods

Nine patients, nine caregivers and three healthcare professionals participated in virtual simulations of planned phase III trials. During the simulations, participants received information about the trials and either tested a home spirometry device or watched a home spirometry demonstration, before providing their insights in debriefs. The findings were interpreted in advisory boards with representatives from patient organisations and expert investig

SUBMITTER: Jones S 

PROVIDER: S-EPMC10227627 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature