Evidence for concealed fasciculo-ventricular connections as revealed by His bundle pacing.

ABSTRACT:

Background

It is almost 100 years ago since Mahaim described the so-called paraspecific connections between the ventricular conduction axis and the crest of the muscular ventricular septum, believing such pathways to be ubiquitous. These pathways, however, have yet to be considered as potential pathways for septal activation during His bundle pacing.

Materials

So as to explore the hypothesis that specialised septal pathways might provide the substrate for septal activation during His bundle pacing, we compared the findings from 22 serially sectioned histological datasets and 34 different individuals undergoing His bundle pacing.

Results

We found histologically specialised pathways connecting the branching component of the atrioventricular conduction axis with the cres

SUBMITTER: Mahmud R 

PROVIDER: S-EPMC10227651 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature