Risk factors for hospital-onset Clostridioides difficile infections before and during the severe acute respiratory syndrome coronavirus 2 pandemic.

ABSTRACT: In this retrospective cohort from three Missouri hospitals from January 2017 to August 2020, hospital-onset Clostridioides difficile infections (CDI) were more common during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic at the tertiary care hospital. Risk factors associated with hospital-onset CDI included year of hospitalization, age, high-risk antibiotic use, acid-reducing medications, chronic comorbidities, and SARS-CoV-2 infection.

SUBMITTER: Kwon JH 

PROVIDER: S-EPMC10228158 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature