Impact of prior SARS-COV-2 infection and vaccination on COVID-19 hospital admission and mortality amongst nursing home residents.

ABSTRACT:

Background

Nursing home residents (NHRs) have experienced disproportionately high risk of severe outcomes due to COVID-19 infection.

Aim

We investigated the impact of COVID-19 vaccinations and previous SARS-CoV-2 episodes in preventing hospitalization and mortality in NHRs.

Methods

Retrospective study of a cohort of all NHRs in our area who were alive at the start of the vaccination campaign. The first three doses of SARS-CoV-2 vaccine and prior COVID-19 infections were registered. The main outcomes were hospital admission and mortality during each follow up. Random effects time-varying Cox models adjusted for age, sex, and comorbidities were fitted to estimate hazard ratios (HRs) according to vaccination status.

Results

COVID-19 hospitalization and death rates

SUBMITTER: Espana PP 

PROVIDER: S-EPMC10228436 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature