Comparison of the survival outcomes between primary and secondary muscle-invasive bladder cancer: a propensity score-matched study.

ABSTRACT:

Background

Studies have classified muscle-invasive bladder cancer (MIBC) into primary (initially muscle-invasive, PMIBC) and secondary subtypes (initially non-muscle-invasive but progresses, SMIBC), for which controversial survival outcomes were demonstrated. This study aimed to compare the survival outcomes between PMIBC and SMIBC patients in China.

Methods

Patients diagnosed with PMIBC or SMIBC at West China Hospital from January 2009 to June 2019 were retrospectively included. Kruskal-Wallis and Fisher tests were employed to compare clinicopathological characteristics. Kaplan-Meier curves and Cox competing proportional risk model were used to compare survival outcomes. Propensity score matching (PSM) was employed to reduce the bias and subgroup analysis was used to confir

SUBMITTER: Lok W 

PROVIDER: S-EPMC10228478 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature