Age group differences in learning-related activity reflect task stage, not learning stage.

ABSTRACT: Healthy aging is accompanied by declines in the ability to learn associations between events, even when their relationship cannot be described. Previous functional magnetic resonance imaging (fMRI) studies have attributed these implicit associative learning (IAL) deficits to differential engagement of the hippocampus and basal ganglia in older relative to younger adults in early and late stages of the task, respectively. However, these task stages have been confounded with age group differences in learning performance that emerge later and to a lesser degree in older adults. To disentangle the effects of task stage from learning stage (i.e., when there is significant evidence of learning) on age group differences in the neural substrates of IAL, we acquired fMRI data while 28 younger (20.8

SUBMITTER: Merenstein JL 

PROVIDER: S-EPMC10228494 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature