The Gal/GalNac lectin as a possible acetylcholine receptor in Entamoeba histolytica.

ABSTRACT: Entamoeba histolytica (E. histolytica) is a protozoan responsible for intestinal amebiasis in at least 500 million people per year, although only 10% of those infected show severe symptoms. It is known that E. histolytica captures molecules released during the host immune response through membrane receptors that favor its pathogenetic mechanisms for the establishment of amebic invasion. It has been suggested that E. histolytica interacts with acetylcholine (ACh) through its membrane. This promotes the increase of virulence factors and diverse mechanisms carried out by the amoeba to produce damage. The aim of this study is to identify a membrane receptor in E. histolytica trophozoites for ACh. Methods included identification by colocalization for the ACh a

SUBMITTER: Pacheco-Sanchez M 

PROVIDER: S-EPMC10228505 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature