Personalized pulmonary vein antrum isolation guided by left atrial wall thickness for persistent atrial fibrillation.

ABSTRACT:

Aims

Pulmonary vein (PV) antrum isolation proved to be effective for treating persistent atrial fibrillation (PeAF). We sought to investigate the results of a personalized approach aimed at adapting the ablation index (AI) to the local left atrial wall thickness (LAWT) in a cohort of consecutive patients with PeAF.

Methods and results

Consecutive patients referred for PeAF first ablation were prospectively enrolled. The LAWT three-dimensional maps were obtained from pre-procedure multidetector computed tomography and integrated into the navigation system. Ablation index was titrated according to the local LAWT, and the ablation line was personalized to avoid the thickest regions while encircling the PV antrum. A total of 121 patients (69.4% male, age 64.5 ± 9.5 years) were i

SUBMITTER: Falasconi G 

PROVIDER: S-EPMC10228614 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature