Dynamic contrast-enhanced computed tomography in dogs with nasal tumors.

ABSTRACT:

Background

Treatment of nasal tumors in dogs is associated with high morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion.

Objectives

To assess perfusion parameters of nasal tumors (correlating with tumor type) before and during radiotherapy (RT) and find potential correlation with survival.

Animals

Twenty-four client-owned dogs with nasal tumors, including 16 epithelial tumors and 8 sarcomas.

Methods

Prospective cross-sectional study. All dogs had baseline DCECT to assess fractional vascular volume (BV), blood flow (BF), and transit time (TT). Thirteen dogs had repeat DCECT after 12 Gy of megavoltage RT. Survival times were calculated.

Results

Median BV was 17.

SUBMITTER: Mortier JR 

PROVIDER: S-EPMC10229329 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature