Hemostatic profiles in dogs with sudden acquired retinal degeneration syndrome.

ABSTRACT:

Background

Sudden acquired retinal degeneration syndrome (SARDS) is a common cause of irreversible blindness in dogs. It bears clinical resemblance to hypercortisolism, which can be associated with hypercoagulability. The role of hypercoagulability in dogs with SARDS is unknown.

Objective

Determine hemostatic profiles in dogs with SARDS.

Animals

Prospective pilot study: Dogs with a history of SARDS (n = 12). Prospective case-control study: Dogs with recent onset of SARDS (n = 7) and age-, breed-, and sex-matched controls (n = 7).

Methods

Prospective pilot study: We performed thromboelastography (TEG). Prospective case-control study: Dogs had CBC, serum biochemistry, urinalysis, TEG, fibrinogen concentration, antithrombin activity, D-dimers, thrombin-antithrombi

SUBMITTER: Lynch AM 

PROVIDER: S-EPMC10229342 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature