Fungal β-glucan-facilitated cross-feeding activities between Bacteroides and Bifidobacterium species.

ABSTRACT: The human gut microbiota (HGM) is comprised of a very complex network of microorganisms, which interact with the host thereby impacting on host health and well-being. β-glucan has been established as a dietary polysaccharide supporting growth of particular gut-associated bacteria, including members of the genera Bacteroides and Bifidobacterium, the latter considered to represent beneficial or probiotic bacteria. However, the exact mechanism underpinning β-glucan metabolism by gut commensals is not fully understood. We show that mycoprotein represents an excellent source for β-glucan, which is consumed by certain Bacteroides species as primary degraders, such as Bacteroides cellulosilyticus WH2. The latter bacterium employs two extracellular, endo-acting enzymes, belonging to glycoside hydr

SUBMITTER: Fernandez-Julia P 

PROVIDER: S-EPMC10229575 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature