Effects of schema on the relationship between post-encoding brain connectivity and subsequent durable memory.

ABSTRACT: Schemas can facilitate memory consolidation. Studies have suggested that interactions between the hippocampus and the ventromedial prefrontal cortex (vmPFC) are important for schema-related memory consolidation. However, in humans, how schema accelerates the consolidation of new information and relates to durable memory remains unclear. To address these knowledge gaps, we used a human analogue of the rodent spatial schema task and resting-state fMRI to investigate how post-encoding brain networks can predict long-term memory performance in different schema conditions. After participants were trained to obtain schema-consistent or schema-inconsistent object-location associations, they learned new object-location associations. The new associations were tested after the post-encoding rest in

SUBMITTER: Guo D 

PROVIDER: S-EPMC10229577 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature