EVELUT®: A Real-World, Observational Study Assessing Dyspnoea and Symptom Burden in COPD Patients Switched from LABA/ICS to LAMA/LABA or LAMA/LABA/ICS.

ABSTRACT:

Introduction

The Global Initiative for Chronic Obstructive Lung Disease (GOLD 2023) no longer recommends a long-acting β₂-agonist (LABA) plus inhaled corticosteroid (ICS) combination for the treatment of chronic obstructive pulmonary disease (COPD). In patients treated with LABA/ICS, who continue to experience symptoms without frequent or severe exacerbations, GOLD now recommends switching to long-acting muscarinic antagonist (LAMA)/LABA instead of escalating to triple therapy (TT; LAMA/LABA/ICS), which previously was also a recommended option. EVELUT^®, a real-life, observational study, compared these two treatment strategies in terms of symptom relief and health status improvement.

Methods

Patients with symptomatic COPD at low exacerbation risk (GOLD B

SUBMITTER: Buhl R 

PROVIDER: S-EPMC10230142 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature