Necroptosis has a crucial role in the development of chronic periodontitis.

ABSTRACT:

Background and aim

Periodontitis is a non-communicable chronic inflammatory disease that affects the entire periodontium and its severe types cause irreparable destruction. The purpose of this study was to determine the type of cell death in chronic periodontitis (CP) with the expression of receptor-interacting protein kinase (RIPK) type1 and RIPK3 genes.

Materials and methods

This cross-sectional study was carried out from September 2019 to 2020. The samples (38 participants) were divided into two groups: 20 recently diagnosed CP patients and 18 healthy individuals. Participants' data was collected in the periodontology Department, Dental school, Mashhad University of Medical Sciences and sent to the Immunology Lab for assessment of RIPK1 and RIPK3 expressions using quantit

SUBMITTER: Akhondian S 

PROVIDER: S-EPMC10230260 | biostudies-literature | 2023 Jul-Aug

REPOSITORIES: biostudies-literature