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Intratumoral injection therapies for locally advanced pancreatic cancer: systematic review.


ABSTRACT:

Introduction

Pancreatic cancer has one of the worst prognoses of all cancers. Patients with locally advanced pancreatic cancer have a 12.7-20.2 per cent chance of receiving curative surgery after induction systemic chemotherapy. Intratumoral injection therapies have been studied as complementary treatment options for improved local tumour control. The aim of this systematic review was to provide an overview of intratumoral injection therapies, their safety, and oncological outcome in patients with locally advanced pancreatic cancer.

Methods

A literature search was conducted in PubMed, Embase and the Cochrane Library for articles written in English up to 28 November 2022. All study designs involving at least five patients with locally advanced pancreatic cancer who were treat

SUBMITTER: Willink CY 

PROVIDER: S-EPMC10230443 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature