Linking the region-specific tissue microstructure to the biaxial mechanical properties of the porcine left anterior descending artery.

ABSTRACT: Coronary atherosclerosis is the main cause of death worldwide. Advancing the understanding of coronary microstructure-based mechanics is fundamental for the development of therapeutic tools and surgical procedures. Although the passive biaxial properties of the coronary arteries have been extensively explored, their regional differences and the relationship between tissue microstructure and mechanics have not been fully characterized. In this study, we characterized the passive biaxial mechanical properties and microstructural properties of the proximal, medial, and distal regions of the porcine left anterior descending artery (LADA). We also attempted to relate the biaxial stress-stretch response of the LADA and its respective birefringent responses to the polarized light for obtaining in

SUBMITTER: Pineda-Castillo SA 

PROVIDER: S-EPMC10230544 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature