Effect of miR-149-5p on intramuscular fat deposition in pigs based on metabolomics and transcriptomics.

ABSTRACT: As one of the important traits in pig production, meat quality has important research significance and value. Intramuscular fat (IMF) content is one of the most important factors affecting pork quality. Many experimental studies have shown that IMF content is closely related to the flavor, tenderness, and juiciness of pork. Therefore, it is of great significance to study the mechanism of porcine IMF deposition. Previous research indicated that miR-149-5p promoted the proliferation of porcine intramuscular (IM) preadipocytes and decreased their ability to differentiate, albeit the exact mechanism of action is unknown. In vitro, foreign pigs showed increased miR-149-5p expression and reduced fat deposition when compared to Queshan Black pigs. This study conducted metabolomics and transcripto

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10230699 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature