The effect of CPAP on the upper airway and ventilatory flow in patients with obstructive sleep apnea.

ABSTRACT:

Background

Continuous positive airway pressure (CPAP) is the mainstay of treatment for obstructive sleep apnea (OSA). However, data about its effect on the upper airway, especially the epiglottis, are scarce. The aim of this study was to investigate the changes in upper airway dimensions and inspiratory flow in response to incremental pressure levels.

Methods

This is a secondary analysis of a prospective clinical trial in which patients with moderate to severe OSA underwent drug-induced sleep endoscopy with simultaneous recordings of flow and mask pressure. CPAP was titrated in small increments. For each pressure level a representative 3-breath segment was selected to determine specific flow features. The corresponding endoscopic footage was reviewed to assess the degree of

SUBMITTER: Van de Perck E 

PROVIDER: S-EPMC10230814 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature