Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.

ABSTRACT:

Objective

To compare the performance of a newly developed race-free kidney recipient specific glomerular filtration rate (GFR) equation with the three current main equations for measuring GFR in kidney transplant recipients.

Design

Development and validation study SETTING: 17 cohorts in Europe, the United States, and Australia (14 transplant centres, three clinical trials).

Participants

15 489 adults (3622 in development cohort (Necker, Saint Louis, and Toulouse hospitals, France), 11 867 in multiple external validation cohorts) who received kidney transplants between 1 January 2000 and 1 January 2021.

Main outcome measure

The main outcome measure was GFR, measured according to local practice. Performance of the GFR equations was assessed using P₃₀ (

SUBMITTER: Raynaud M 

PROVIDER: S-EPMC10231444 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature