Mechanical bowel preparation and antibiotics in elective colorectal surgery: network meta-analysis.

ABSTRACT:

Background

The use of intravenous antibiotics at anaesthetic induction in colorectal surgery is the standard of care. However, the role of mechanical bowel preparation, enemas, and oral antibiotics in surgical site infection, anastomotic leak, and other perioperative outcomes remains controversial. The aim of this study was to determine the optimal preoperative bowel preparation strategy in elective colorectal surgery.

Methods

A systematic review and network meta-analysis of RCTs was performed with searches from PubMed/MEDLINE, Scopus, Embase, and the Cochrane Central Register of Controlled Trials from inception to December 2022. Primary outcomes included surgical site infection and anastomotic leak. Secondary outcomes included 30-day mortality rate, ileus, length of stay, r

SUBMITTER: Tan J 

PROVIDER: S-EPMC10231808 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature