Neurophysiological mechanisms of error monitoring in human and non-human primates.

ABSTRACT: Performance monitoring is an important executive function that allows us to gain insight into our own behaviour. This remarkable ability relies on the frontal cortex, and its impairment is an aspect of many psychiatric diseases. In recent years, recordings from the macaque and human medial frontal cortex have offered a detailed understanding of the neurophysiological substrate that underlies performance monitoring. Here we review the discovery of single-neuron correlates of error monitoring, a key aspect of performance monitoring, in both species. These neurons are the generators of the error-related negativity, which is a non-invasive biomarker that indexes error detection. We evaluate a set of tasks that allows the synergistic elucidation of the mechanisms of cognitive control across the

SUBMITTER: Fu Z 

PROVIDER: S-EPMC10231843 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature