Clinical and epidemiological profiles from a case series of 26 Brazilian CADASIL patients.

ABSTRACT:

Background

 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic cause of ischemic stroke and the most common form of non-atherosclerotic stroke. Despite being the most prevalent vascular hereditary disease, clinical data regarding the Brazilian population are scarce. Considering that the Brazilian population has one of the most heterogeneous genetic constitutions in the world, knowledge about genetic and epidemiological profiles is mandatory. The present study aimed to elucidate the epidemiological and clinical features of CADASIL in Brazil.

Methods

 We performed a case series study comprising 6 rehabilitation hospitals in Brazil and reported the clinical and epidemiological data from the medical records of patien

SUBMITTER: Nogueira R 

PROVIDER: S-EPMC10232034 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature