Case-control study developing Scottish Epilepsy Deaths Study Score to predict epilepsy-related death.

ABSTRACT: This study aimed to develop a risk prediction model for epilepsy-related death in adults. In this age- and sex-matched case-control study, we compared adults (aged ≥16 years) who had epilepsy-related death between 2009 and 2016 to living adults with epilepsy in Scotland. Cases were identified from validated administrative national datasets linked to mortality records. ICD-10 cause-of-death coding was used to define epilepsy-related death. Controls were recruited from a research database and epilepsy clinics. Clinical data from medical records were abstracted and used to undertake univariable and multivariable conditional logistic regression to develop a risk prediction model consisting of four variables chosen a priori. A weighted sum of the factors present was taken to create a risk index

SUBMITTER: Mbizvo GK 

PROVIDER: S-EPMC10232261 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature