A Retrospective Real-World Observational Study Assessing the Evolution of Bisacodyl Prescriptions in Patients with Constipation During Long-Term Treatment.

ABSTRACT:

Background

Potential habituation could be a safety concern associated with the long-term use of bisacodyl in patients with constipation.

Objective

In this study, we evaluated whether patients with constipation who require long-term treatment with bisacodyl will remain on a stable dose when treated for ≥ 28 days.

Methods

In this retrospective, population-based, observational cohort study, electronic medical record data of adult patients with constipation between January 1, 2011, and December 31, 2019, were collected from The Health Improvement Network French database. Total bisacodyl exposure during the long-term (≥ 28 days) and follow-up (12 months) periods was evaluated. The primary endpoint was the dose change status of bisacodyl during the follow-up period from the

SUBMITTER: Bouchoucha M 

PROVIDER: S-EPMC10232381 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature