Polymer bilayer-Micro arc oxidation surface coating on pure magnesium for bone implantation.

ABSTRACT:

Background

Pure magnesium-based ortho-implants have a number of advantages. However, vital parameters like degradation rate and biocompatibility still call for significant improvement.

Methods

In this study, poly (1,3-trimethylene carbonate) (PTMC) and polydopamine (PDA) bilayer and micro arc oxidation composite coatings were prepared successively on magnesium surface by immersion method and microarc oxidation. Its corrosion resistance and biocompatibility were evaluated by in vitro corrosion tests, cellular compatibility experiments, and in vivo animal experiments.

Results

In vitro experiments demonstrated that the composite coating provides excellent corrosion protection and biocompatibility. Animal studies demonstrated that the composite coatin

SUBMITTER: Dong J 

PROVIDER: S-EPMC10232471 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature