NMR resonance assignment of a fibroblast growth factor 8 splicing isoform b.
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ABSTRACT:
SUBMITTER: Hargittay B
PROVIDER: S-EPMC10232571 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Publications
NMR resonance assignment of a fibroblast growth factor 8 splicing isoform b.
Hargittay Bruno B Mineev Konstantin S KS Richter Christian C Sreeramulu Sridhar S Jonker Hendrik R A HRA Saxena Krishna K Schwalbe Harald H
Biomolecular NMR assignments 20230429 1
The splicing isoform b of human fibroblast growth factor 8 (FGF8b) is an important regulator of brain embryonic development. Here, we report the almost complete NMR chemical shift assignment of the backbone and aliphatic side chains of FGF8b. Obtained chemical shifts are in good agreement with the previously reported X-ray data, excluding the N-terminal gN helix, which apparently forms only in complex with the receptor. The reported data provide an NMR starting point for the investigation of FGF ...[more]
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