Associations of Health-Related Quality of Life and Sleep Disturbance With Cardiovascular Disease Risk in Postmenopausal Breast Cancer Survivors.

ABSTRACT:

Background

Breast cancer (BC) survivors are at an increased risk of long-term cardiovascular disease (CVD), often attributed to cancer treatment. However, cancer treatment may also negatively impact health-related quality of life (HRQoL), a risk factor of CVD in the general population.

Objective

We examined whether sleep disturbance, and physical or mental HRQoL were associated with CVD risk in BC survivors.

Methods

We conducted a longitudinal analysis in the Women's Health Initiative of postmenopausal women given a diagnosis of invasive BC during follow-up through 2010 with no history of CVD before BC. The primary outcome was incident CVD, defined as physician-adjudicated coronary heart disease or stroke, after BC. Physical and mental HRQoL, measured by the Short-For

SUBMITTER: Vasbinder A 

PROVIDER: S-EPMC10232669 | biostudies-literature | 2023 Nov-Dec 01

REPOSITORIES: biostudies-literature