Pan-cancer analysis identifies the correlations of Thymosin Beta 10 with predicting prognosis and immunotherapy response.

ABSTRACT:

Introduction

The biological function and prognosis roles of thymosin β(TMSB) 10 are still unclear in pan-cancer.

Methods

We retrieved The Cancer Genome Atlas and Genotype-tissue expression datasets to obtain the difference of TMSB10 expression between pan-cancer and normal tissues, and analyzed the biological function and prognosis role of TMSB10 in pan-cancer by using cBioPortal Webtool.

Results

The expression of TMSB10 in tumor tissues was significantly higher than normal tissues, and showed the potential ability to predict the prognosis of patients in Pan-cancer. It was found that TMSB10 was significantly correlated with tumor microenvironment, immune cell infiltration and immune regulatory factor expression. TMSB10 is involved in the regulation of cellular signal

SUBMITTER: Li Z 

PROVIDER: S-EPMC10232749 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature