A nomogram model to predict the risk of drug-induced liver injury in patients receiving anti-tuberculosis treatment.

ABSTRACT: Objectives: To establish an individualized nomogram to predict the probability of drug-induced liver injury (DILI) in tuberculosis patients receiving anti-tuberculosis treatment. Methods: The clinical information of patients admitted to a tertiary hospital between January 2010 and December 2022 was retrospectively reviewed from the clinical records. Patients with baseline liver diseases (hepatis B or C infection and fatty liver) or taking liver protective drugs were excluded. The maximum values in liver function test within 180 days after anti-tuberculosis treatment were collected to determine the occurrence of DILI. The candidate variables used for establishing prediction model in this study were the last results within the 30 days before the treatment onset. The final varia

SUBMITTER: Ji S 

PROVIDER: S-EPMC10232814 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature