Cortical depth-dependent human fMRI of resting-state networks using EPIK.

ABSTRACT:

Introduction

Recent laminar-fMRI studies have substantially improved understanding of the evoked cortical responses in multiple sub-systems; in contrast, the laminar component of resting-state networks spread over the whole brain has been less studied due to technical limitations. Animal research strongly suggests that the supragranular layers of the cortex play a critical role in maintaining communication within the default mode network (DMN); however, whether this is true in this and other human cortical networks remains unclear.

Methods

Here, we used EPIK, which offers unprecedented coverage at sub-millimeter resolution, to investigate cortical broad resting-state dynamics with depth specificity in healthy volunteers.

Results

Our results suggest that

SUBMITTER: Pais-Roldan P 

PROVIDER: S-EPMC10232833 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature