Toxicological effects of micro/nano-plastics on mouse/rat models: a systematic review and meta-analysis.

ABSTRACT: Micro/nano-plastics (MNPs) are considered a heterogeneous class of environmental contaminants that cause multiple toxic effects on biological species. As the commonly used mammalian models to study the effects of MNPs with regard to their toxic effects, the mouse and rat models are making a great contribution to the disciplines of environmental toxicology and medical health. However, the toxic effects of MNPs have not been systematically summarized. Therefore, a systematic review and a meta-analysis of the toxic effects of MNPs on mouse/rat models were conducted. A total of seven main categories were established in this systematic review, and 24 subcategories were further divided according to the specific physiological significance of the endpoint or the classification of the physiological

SUBMITTER: Liu W 

PROVIDER: S-EPMC10233117 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature